---
title: Per Sample Bioinformatics Analysis Services
description: Bioinformatics data analysis services for gene expression, variant calling, protein dna interaction, epigenetics, metagenomics, proteomics and microarray
---
[](https://www.onramp.bio)
[](https://www.onramp.bio)
Streamline your Research from Experimental Design to Interpretation
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/0aeae9eb-a21c-43ac-a158-6df58aa869cd)
## Our services
Our scientific team is powered by our proprietary software that enables faster and more simplified analyses of NGS data.
##### Experiment Design
1:1 Consulting and expert guidance for efficient and targeted experiment design with our team:
- Design your experiment to efficiently achieve your objectives
- Avoid frequent technical and scientific pitfalls with improperly designed genomic experiments
- Select the most cost-effective and appropriate technologies to generate optimal data (next-generation sequencing, microarrays, panels, mass spec, etc)
- Start your project with full confidence after feedback and review from our team of experts
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/dbc88484-9b71-49a8-8a27-1b8c60b603e6)
##### GENOMICS-FOCUSED IT Consulting
Custom BioInformatics Analyses, Private Cloud, or
On-Premise IT Solutions:
- Design and deploy private cloud, or on-premise software and storage solutions
- Strategic guidance from our bioInformatics and big data technology experts on software and system architecture, as well as robust IT and data provenance solutions
- Advanced bioinformatics consulting and custom analyses for any project type
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/da1a87af-d363-4e4f-9831-955b88ad24f9)
##### RNA-Seq Data Analysis and Interpretation
Comprehensive gene expression profiling and analysis:
- Rapid analysis of raw RNA-seq reads, miRNA or microarray data to gain insights into target genes, and overall expression levels
- Comprehensive analysis of upregulated and downregulated genes
- Differentially expressed genes across samples, time series, treatments or any condition or criteria
- Sort, filter and identify key patterns and pathways in highly expressed gene signatures
- Collaborate and share results across any extended research team
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/56702ca5-f03c-45e9-a266-29629283413c)
##### Single cell gene expression analysis
Comprehensive analysis of single cell gene expression:
- Rapid analysis of raw RNA-seq reads to gain insights into target genes, and overall expression levels
- Comprehensive analysis of upregulated and downregulated genes
- Differentially expressed genes across samples, time series, treatments or any condition or criteria
- *De novo *identification of unique cell sub-populations
- Sort, filter and identify key patterns and pathways in highly expressed gene signatures
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/61a665b8-5a4d-4c02-a6d0-cb4ad0be3efc)
##### Protein-DNA Interaction Analysis
Comprehensive ChIP analysis:
- Rapid analysis of raw chromatin immunoprecipitation sequencing ChIP-seq reads to identify regions of protein interaction with DNA
- Annotate and analyze motifs on the predicted binding regions
- Differential analysis of binding between conditions
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/7202d400-83d1-4ec9-b4bc-c052219d5323)
##### Whole Genome / Exome Data Analysis
Advanced analysis and visual analytics for Whole Genome Sequencing:
- Rapid analysis of raw DNA-seq reads to identify single nucleotide variants (SNVs)
- Analysis for single genome, trios, cohorts, or tumor-normal pairs
- Industry standard tools published in peer-reviewed journals
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/6721ea28-64e2-4964-97a9-452932ff1970)
##### Methylation analysis
Comprehensive differential methylation data analysis:
- Rapid analysis of raw Methyl-seq or reduced representation bisulfite sequencing (RRBS) reads to identify methylation sites
- Differential methylation analysis between conditions
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/d1834803-f993-442c-8ef8-889d9c869d21)
##### Microarray & Mass Spec Data Analysis
Comprehensive bioinformatics analysis:
- Full range of analysis and annotations for any type of microarrays (Gene expression, miRNA, SNP, CNV, CGH, methylation, protein...), or mass spectrometry instruments
- Variant calling and interpretation for whole genome, exome or targeted studies
- Methylation sites for epigenetics studies
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/d24fc386-efe8-4ba5-833f-3756d5205fdf)
##### Metagenomics Data Analysis
Comprehensive metagenomics data analysis:
- Rapid analysis of 16s or shotgun metagenomics data files
- Gain insight into communities of microorganisms found in environmental samples
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/7e8f4d5c-fe63-4e68-8f57-c026e06d0154)
##### Metatranscriptomics Data Analysis
Comprehensive metatranscriptomics data analysis:
- Gain insight into genes expressed in environmental samples
[](https://cta-redirect.hubspot.com/cta/redirect/2296042/9c7f2cc7-1682-4429-8e33-45906b014302)
5240
Workflow Runs
250
TB of DATA GENERATED
2507
AnalysES COMPLETED
100457
GENOMIC FILES CREATED
I've had the opportunity to work closely with the Onramp team for the last two years. Together we have completed hundreds of analyses. Their software solutions and team have been instrumental to advancing our research at MUSC. Jeremy and Roshni on the bioinformatics team are great. They've been responsive and insightful - and even seem like an extension of our team at times!
Dr. Gary Hardiman
Medical University of South Carolina
OnRamp will work with you every step of the way, from project inception, through interfacing with sequencing partners, through developing novel informatics solutions for your project. Their bioinformatics platform has many unique attributes that make it appealing, but their data and analysis tracking is just amazing: provenance for all your analyses from the minute the sequences arrive.
Rob Edwards, Ph.D
San Diego State University
My experience with OnRamp Bioinformatics is nothing but outstanding! They analyzed my datasets quickly and provided a skype meeting to go over all the data. Moreover, the way they organized the data was very logical and easy to follow! I recommend them to anyone needing bioinformatics analysis.
I know I’ll be coming back to them in the future!
Paola Vermeer, Ph.D
Sanford Research
OnRamp Bio empowers researchers, biologists and scientists with genomic answers and insights that they can understand and put to action.
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